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However, due to the need for frequent blood sampling, this approach has been largely replaced by breath testing. Symptoms resolve following eliminating lactose [1]. If the hydrogen levels in the patient's breath are high, they may have lactose intolerance. When lactose intolerance is due to secondary lactase deficiency, treatment of the underlying disease may allow lactase activity to return to normal levels. Before the 20th century, babies born with congenital lactase deficiency often did not survive, [2] but death rates decreased with soybean -derived infant formulas and manufactured lactose-free dairy products. A survey of milk intolerance and lactase deficiency in healthy adult males". This test allows a noninvasive definitive diagnostic.

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